Fukinolic acid and cimicifugic acids: a review

Abstract During the last decades, research on biological activities of extracts from Cimicifuga / Actaea species and Petasites japonicus as well their active ingredients has been intensified. Besides terpenoids dominant natural product group, hydroxycinnamic acid esters such fukinolic several cimicifugic acids have isolated chemical structures elucidated. Investigations properties these are currently undertaken some compounds might be promising therapeutic tools. In this review, we gathered information genera , occurrence aspects biosynthesis. Furthermore, summarized medicinal acids. connection with compounds, structural features derivatives move into focus. The position hydroxyl group at aromatic rings introduction an electron-donating moiety may important for anti-inflammatory, antiviral, cytotoxic vasoactive effects compounds.